Fig. 3

Transcriptome analyses of MM cells transfected with sh-HNRNPA2B1-8226 versus the control sh-NC-8226. A Volcano map of the distribution of differentially expressed genes. Up-regulated genes are shown in red, and down-regulated genes in green. B Histogram distribution of different genes, showing the pathways with the most significant differences. The green bar represents the biological process pathway, the orange represents the cellular component pathway, and the blue indicates the molecular function pathway. C Heatmap of different genes clustered in sh-HNRNPA2B1-8226 and sh-NC-8226. The color from blue to red indicates that log10 (FPKM + 1) is from low to high. D KEGG pathway enrichment results for differentially expressed genes between MM cells transfected with sh-HNRNPA2B1-8226 and control sh-NC-8226