Fig. 7
p-TBC1D1Ser660 promoted malignant activities could be inhibited by FZD7 interference. A, B Cell proliferative capability was determined by CCK-8 (A) and EdU (B) assays. C, D Cell metastatic and invasive capability were determined by wound healing (C) and Transwell (D) assays. E TOP/FOP flash assay was conducted on indicate cells to evaluate the effect of FZD7 on WNT/β-catenin signaling. F Western blot analysis was conducted on indicated cells to evaluate the effect of FZD7 on WNT/β-catenin signaling. Data represent mean ± SD of three independent experiments and were analyzed by two-sided unpaired Student’s t-test, *P < 0.05, **P < 0.01