Fig. 2

MICAL1 promoted PC cell proliferation, invasion, and metastasis in vitro. A–C Cell proliferation of PANC-1 and SW1990 cells with MICAL1 stable overexpression and MICAL1 stable silencing were determined by CCK-8 (A), colony formation (B) and EdU (C) assays. D, E Cell metastasis and invasion of indicated PC cells were determined by wound healing (D) and Transwell (E) assays. Data represent mean ± SD of three independent experiments and were analyzed by two-sided unpaired Student’s t-test, *P < 0.05, **P < 0.01