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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Effects of hydrogen-rich saline in neuroinflammation and mitochondrial dysfunction in rat model of sepsis-associated encephalopathy

Fig. 4

HRS treatment attenuated astrocyte and microglial activation in cerebral cortex and hippocampus of septic rats 48 h after LPS induction. The photographs present immunohistochemistry staining showing the number of GFAP(top diagram) and IBA-1 (bottom) Positive cells in each group, respectively (n = 6). Scale bar = 50 μm. A, B Quantification of GFAP and IBA-1positive cells in cerebral cortex and hippocampus in each group, respectively. All data are presented as mean ± SD ****p < 0.0001, ***p < 0.001, **p < 0.005. HRS Hydrogen-rich saline, LPS lipopolysaccharide, GFAP Glial fibrillary acidic protein, IBA-1 Ionised calcium binding adaptor molecule 1

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