Fig. 5
From: A circular network of purine metabolism as coregulators of dilated cardiomyopathy
The hub markers detection based on XGBoost and SHAP model. A The AUC curves showing the prediction performance of sensitivity, specificity, precision, and recall based on the gene’s expression of purine metabolism pathway. B The bar plot showing the top 15 relative importance features in our ML model. C The SHAP summary plot presenting the SHAP value (relative impact on ML model) of top 15 relative importance features. D The SHAP force plot showing the hub gene contribution to the base value in SHAP model