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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: A circular network of purine metabolism as coregulators of dilated cardiomyopathy

Fig. 2

The differential expression and functional pathway analysis in GSE57338 dataset. A The volcano map showing the differential expressed genes between the control and DCM samples. Green dots are down-regulated DEGs and red dots are up-regulated DEGs. B The GSEA analysis shown the maps of cGMP metabolic process, oxygen transport, NAD metabolic process, linoleic acid metabolic process, long-chain fatty acid binding, and phosphatidylethanolamine metabolic process were significantly enriched. The color bar indicates the corrected p value of the enrichment pathway. The size of the dot indicates the number of enriched genes. C The heatmap showing the patterns of the GSVA score of the KEGG pathway, and the metabolism- related maps were significantly identified. D The purine metabolism- related maps were detected based on GSEA analysis

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