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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Integrative analyses of maternal plasma cell-free DNA nucleosome footprint differences reveal chromosomal aneuploidy fetuses gene expression profile

Fig. 4

Dysregulated immune genes detected in maternal serum in trisomic pregnancies. Cell-free DNA nucleosome coverage (Z-scored original value) of six selected immune genes with significant difference between healthy pregnancies and different trisomic pregnancies. The extremes of the boxes define the upper and lower quartiles, and the center lines define the median. Whiskers indicate 1.5 times the interquartile range (IQR). The value on the boxplot was the depth of these immune genes in the TSS region of the cfDNA of different trisomic pregnancies, respectively

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