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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Anthocyanin improves kidney function in diabetic kidney disease by regulating amino acid metabolism

Fig. 4

Metabolic profiles in the kidney and serum in DKD. The score plot of Orthogonal projections to latent structures discriminant analysis (OPLS-DA) for distinguishing metabolites in the kidney (A) and serum (D) between the DKD and CT groups. The OPLS-DA model for distinguishing metabolites in the kidney (B) and serum (E) between the DKD and CT groups. The upset plot for differentially expressed metabolites in the kidney (C) and serum (F) between the DKD and CT groups. Bubble plot for Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis in the kidney (G) and serum (H) (P < 0.05). The differentially activated KEGG pathways between the DKD and CT groups in the kidney (I) and serum (J). The red and blue bands represent the upregulated and downregulated pathways, respectively (moderated t-test, P < 0.05, |t value|> 2)

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