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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Single-cell RNA sequencing reveals rebalancing of immunological response in patients with periodontitis after non-surgical periodontal therapy

Fig. 6

Circle plot and expression level of RESISTIN signaling pathway

A-C. Circle plot of RESISTIN signaling in the healthy (A), pre-treatment (B), and post-treatment (C) groups, similar to Fig. 4 A‒C. The edge width corresponds to the strength of the ligand‒receptor pairs

D. Relative contribution of ligand-receptor pairs for RESISTIN signaling pathway

E. Violin plot of RETN expression levels in monocytes. The horizontal line indicates the average in each group, and the asterisks denote the significance of the difference between groups calculated using the Wilcoxon rank-sum test. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***), p ≤ 0.0001 (****), p ≥ 0.05 (ns)

F. Proportion of RETN+ monocytes in the healthy, pre- and post-treatment groups

G. Violin plot of RETN expression levels in mDCs. The horizontal line indicates the average in each group, and the asterisks denote the significance of the difference between groups calculated using the Wilcoxon rank-sum test. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***), p ≤ 0.0001 (****), p ≥ 0.05 (ns)

H. Proportion of RETN+ mDCs in the healthy, pre- and post-treatment groups

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