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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Single-cell RNA sequencing reveals rebalancing of immunological response in patients with periodontitis after non-surgical periodontal therapy

Fig. 5

Circle plot and expression level of IFNG signaling pathway

A. Circle plot of IFNG signaling in the pre-treatment group, similar to Fig. 4 A‒C. The edge width corresponds to the strength of the ligand-receptor pairs

B. Violin plot of IFNG expression levels. The horizontal line indicates the average in each group, and the asterisks denote the significance of the difference between groups calculated using the Wilcoxon rank-sum test. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***), p ≤ 0.0001 (****), p ≥ 0.05 (ns)

C. Proportion of IFNG+ NK cells in the healthy, pre- and post-treatment groups

D. Average expression of cytokines including IL1, IL12, IL23, and TNF-α in dendritic cells by condition and IFNG receptor expression. The horizontal line indicates the average in each group, and asterisks denote the significance of the difference between groups calculated using the Wilcoxon rank-sum test. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***), p ≤ 0.0001 (****), p ≥ 0.05 (ns)

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