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Table 2 The tag SNPs of each haplotype block

From: Genome-wide association study reveals ethnicity-specific SNPs associated with ankylosing spondylitis in the Taiwanese population

Block

SNP

Gene

A1/A2a

MAF

MAF case

MAF control

MAF CHS

ORb

95% CIb

P valueb

1

rs142577772

GNL1

T/C

0.085

0.297

0.049

0.033

11.36

(7.18–15.12)

1.45E-34

(3’ UTR)

2

rs7756294

–

A/G

0.131

0.381

0.089

0.067

8.31

(5.95–11.76)

7.48E-33

(intergenic)

3

rs2073716

CCHCR1

G/C

0.206

0.432

0.168

0.186

3.92

(2.79–4.80)

7.56E-21

(intron)

4

rs76977405

–

G/T

0.110

0.372

0.066

0.043

15.27

(9.27–19.45)

1.67E-42

(intergenic)

5

rs7766452

HLA-B

A/G

0.088

0.372

0.041

0.014

34.17

(17.73–41.22)

1.72E-51

(intron)

6

rs9368671

HLA-B

T/C

0.300

0.504

0.266

0.219

3.40

(2.54–4.33)

9.82E-19

(intron)

7

rs28862571

HLA-B

T/C

0.151

0.415

0.107

0.086

10.14

(6.43–12.75)

2.35E-36

(intron)

8

rs9266267

–

C/A

0.123

0.392

0.078

0.057

20.68

(13.20–29.62)

8.23E-46

(intergenic)

9

rs6936035

AL671883.3

G/A

0.286

0.556

0.241

0.195

4.46

(3.81–6.83)

7.33E-25

(intron)

10

rs2251396

MICA

A/G

0.314

0.517

0.280

0.286

3.33

(2.37–3.94)

6.43E-19

(intron)

11

rs3094228

HCP5

C/T

0.229

0.458

0.190

0.138

4.36

(3.19–5.65)

1.19E-22

(intron)

12

rs9688839

HCP5

G/A

0.169

0.364

0.136

0.086

4.18

(2.74–4.78)

1.07E-21

(intron)

  1. aA1 = minor allele, A2 = major allele
  2. bThe ORs, 95% CIs and P values presented in the table are calculated based on data from the combined study