Table 1 Characterization of participants
Baseline Variable | GWAS study | P value | Replication Study | P value | P value | |||
|---|---|---|---|---|---|---|---|---|
Case | Control | Case | Control | Case | Control | |||
n = 118 (%) | n = 698 (%) | n = 81 (%) | n = 505 (%) | 0.936 | 0.113 | |||
Sex | 9.23E-09 | 4.24E-08 | ||||||
Male | 88 (74.6) | 321 (46.0) | 61 (75.3) | 209 (41.4) | ||||
Female | 30 (25.4) | 377 (54.0) | 20 (24.7) | 296 (58.6) | ||||
Age (y, mean ± sd) | 39.63 ± 11.66 | 49.94 ± 16.11 | 1.04E-14 | 39.32 ± 13.95 | 44.72 ± 16.63 | 0.001 | 0.762 | 6.54E-08 |
Age (y) Range | 1.26E-10 | 0.018 | 0.102 | 6.12E-10 | ||||
 < 20 | 0 (0.0) | 12 (1.7) | 0 (0.0) | 9 (1.8) | ||||
20–29 | 20 (16.9) | 68 (9.7) | 25 (30.9) | 102 (20.2) | ||||
30–39 | 42 (35.6) | 112 (16.0) | 24 (29.6) | 116 (23) | ||||
40–49 | 34 (28.8) | 139 (19.9) | 16 (19.8) | 77 (15.2) | ||||
50–59 | 12 (10.2) | 173 (24.8) | 8 (9.9) | 77 (15.2) | ||||
60–69 | 10 (8.5) | 123 (17.6) | 6 (7.4) | 96 (19.0) | ||||
≧70 | 0 (0.0) | 71 (10.2) | 2 (2.5) | 28 (5.5) | ||||
HLA-B27 ( +)a | 76 (77.6) | – | – | 56 (73.7) | – | – | ||