Fig. 7

The over-expression ofAnxa2reversed the inhibitory effects of p-STAT3 on pyroptosis and fibrosis in LPS-treated hepatocytes. (A) WB for detecting the expressions of p-STAT3, ANXA2, pyroptosis-related proteins (ASC, pro-Caspase1, C-Caspase1, GSDMD, and GSDMD-N) and α-SMA. (B) The level of ALT, AST, IL-1β, and CRP in the supernatant of LPS-treated hepatocytes. All cellular experiments were independently repeated three times. **: P < 0.01; ***: P < 0.001