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Table 2 five association metabolites passed all the sensitivity analyses

From: Causality of genetically determined metabolites on anxiety disorders: a two-sample Mendelian randomization study

Description

Pfixed-effect IVW

PMR-Egger

PWeighted-median

PMR-PRESSO

PMR-PRESSO Global

PMR-Egger intercept

PIVW. Q

1-arachidonoylglycerophosphocholine for anxiety disorders diagnosed by psychiatrists

0.0042**

0.026*

0.0002***

0.0096**

0.149

0.338

0.207

androsterone sulfate for anxiety disorders diagnosed by psychiatrists

0.0065**

0.0185*

7.63 × 10–5***

0.0136*

0.113

0.311

0.091

1-linoleoylglycerophosphoethanolamine for anxiety disorders diagnosed by general practitioners

0.002**

0.0148*

0.0001***

0.003**

0.366

0.146

0.408

1-eicosatrienoylglycerophosphocholine for anxiety disorders diagnosed by general practitioners

0.001**

0.0447*

0.116

0.0005***

0.696

0.440

0.670

epiandrosterone sulfate for self-reported anxiety

0.0028**

0.023*

0.0027**

0.007**

0.554

0.249

0.620

  1. *p < 0.05
  2. **p < 0.01
  3. ***p < 0.001;