Fig. 1

TMA/TMAO balance. a the amount of TMA consumed per day; b the amount of TMA excreted per day; c the amount of TMAO excreted per day in rats maintained either on tap water (control group) or low and high dose of TMA. TMA, trimethylamine; TMAO, trimethylamine oxide. All data are expressed as the median (n = 9); Kruskal–Wallis test followed by post-hoc Dunn’s test; ***P < 0.001 vs tap water group; ^###P < 0.001 vs low dose group