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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Transcriptome-based network analysis related to M2-like tumor-associated macrophage infiltration identified VARS1 as a potential target for improving melanoma immunotherapy efficacy

Fig. 2

Functional analysis and differential expression analysis of two clusters. (A) The top 20 enriched KEGG pathways for each cluster were explored by GSVA analysis. (B) Percentage of patients with different TCGA melanoma subtypes in different clusters. (C) GSEA analysis showing that the correlation of clusters with M2 macrophage gene sets. (D) The differences in expression of immune checkpoint-related genes between the two clusters. ‘*’ represents p-value ≤ 0.05, ‘**’ represents p-value ≤ 0.01, ‘***’ represents p-value ≤ 0.001, N.S indicates not significant (p > 0.05)

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Journal of Translational Medicine

ISSN: 1479-5876

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