Fig. 4

Predicted 3D conformation of paired peptides. The conformation of the TAAs and paired HIV-1 antigens and consensus bound to the indicated HLA molecules is shown. The prediction was performed using as template structure peptides crystallized with indicated HLA molecules. Only for HLA-A*02:01, HLA-A*01:01 and HLA-B*07:02 information about the β2 microglobulin, the α and β chains of the T cell receptor (TCR) were available (PDB https://www.rcsb.org/structure/1AO7, 5BRZ, 6VMX). Green areas = contact points with HLA molecule; Blue areas = contact points with the TCR α chain; Violet areas = contact points with the TCR β chain