Combined association of triglyceride-glucose index and systolic blood pressure with all-cause and cardiovascular mortality among the general population

Table 4 Univariate and multivariate Cox regression analysis of the combined association of TyG index and SBP (140 mmHg) with all-cause and cardiovascular mortality

Variables	Mortality rate (per 100,000 person-years)	Univariate analysis	P-value	Multivariate analysis	P-value
Variables	Mortality rate (per 100,000 person-years)	HR (95% CI)	P-value	HR (95% CI)	P-value
All-cause mortality
TyG category
≥ 8.86 (High)	518	Ref.		Ref.
< 8.86 (Low)	257	0.48 (0.37, 0.63)	< 0.001	0.55 (0.39, 0.78)	0.002
SBP category
≥ 140 mmHg	512	Ref.		Ref.
< 140 mmHg	321	0.63 (0.38, 1.05)	0.126	0.75 (0.42, 1.31)	0.354
Combined variables
High TyG, SBP ≥ 140 mmHg	465	Ref.		Ref.
High TyG, SBP < 140 mmHg	522	1.16 (0.50, 2.71)	0.678	1.23 (0.48, 3.11)	0.650
Low TyG, SBP ≥ 140 mmHg	541	1.16 (0.42, 3.22)	0.831	1.27 (0.41, 3.91)	0.745
Low TyG, SBP < 140 mmHg	244	0.53 (0.23, 1.22)	0.071	0.62 (0.24, 1.61)	0.261
P for trend		< 0.001		< 0.001
Cardiovascular mortality
TyG category
≥ 8.55 (High)	69	Ref.		Ref.
< 8.55 (Low)	39	0.42 (0.20, 0.88)	0.037	0.58 (0.31, 0.96)	0.044
SBP category
≥ 140 mmHg	104	Ref.		Ref.
< 140 mmHg	50	0.44 (0.14, 1.42)	0.309	0.51 (0.18, 1.43)	0.308
Combined variables
High TyG, SBP ≥ 140 mmHg	36	Ref.		Ref.
High TyG, SBP < 140 mmHg	71	1.81 (0.14, 22.90)	0.568	2.75 (0.22, 34.17)	0.326
Low TyG, SBP ≥ 140 mmHg	196	4.14 (0.25, 67.60)	0.298	8.06 (0.54, 121.25)	0.092
Low TyG, SBP < 140 mmHg	33	0.61 (0.05, 8.09)	0.667	0.88 (0.10, 16.29)	0.818
P for trend		0.011		0.029

Model adjusted for age, gender, BMI, physical activity, HR, current smoker, diabetes, antihypertensive drugs, glucose-lowering drugs, LDL-C, HDL-C, UA, eGFR

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