Combined association of triglyceride-glucose index and systolic blood pressure with all-cause and cardiovascular mortality among the general population

Table 2 Univariate and multivariate Cox regression analysis of the combined association of TyG index and SBP (120 mmHg) with all-cause and cardiovascular mortality

Variables	Mortality rate (per 100,000 person-years)	Univariate analysis	P-value	Multivariate analysis	P-value
Variables	Mortality rate (per 100,000 person-years)	HR (95% CI)	P-value	HR (95% CI)	P-value
All-cause mortality
TyG category
≥ 8.86 (High)	518	Ref.		Ref.
< 8.86 (Low)	257	0.48 (0.37, 0.63)	< 0.001	0.55 (0.39, 0.78)	0.002
SBP category
≥ 120 mmHg	500	Ref.		Ref.
< 120 mmHg	209	0.42 (0.31, 0.55)	< 0.001	0.48 (0.34, 0.67)	0.001
Combined variables
High TyG, SBP ≥ 120 mmHg	655	Ref.		Ref.
High TyG, SBP < 120 mmHg	361	0.56 (0.36, 0.87)	0.049	0.55 (0.33, 0.91)	0.051
Low TyG, SBP ≥ 120 mmHg	412	0.62 (0.44, 0.87)	0.028	0.62 (0.41, 0.94)	0.023
Low TyG, SBP < 120 mmHg	165	0.25 (0.17, 0.36)	< 0.001	0.29 (0.18, 0.46)	< 0.001
P for trend		< 0.001		< 0.001
Cardiovascular mortality
TyG category
≥ 8.55 (High)	69	Ref.		Ref.
< 8.55 (Low)	39	0.42 (0.20, 0.88)	0.037	0.58 (0.31, 0.96)	0.044
SBP category
≥ 120 mmHg	99	Ref.		Ref.
< 120 mmHg	20	0.17 (0.07, 0.39)	< 0.001	0.28 (0.14, 0.55)	0.001
Combined variables
High TyG, SBP ≥ 120 mmHg	109	Ref.		Ref.
High TyG, SBP < 120 mmHg	27	0.23 (0.07, 0.71)	0.021	0.46 (0.19, 1.07)	0.094
Low TyG, SBP ≥ 120 mmHg	86	0.59 (0.26, 1.37)	0.263	0.79 (0.46, 1.97)	0.907
Low TyG, SBP < 120 mmHg	16	0.09 (0.03, 0.29)	< 0.001	0.16 (0.05, 0.46)	< 0.001
P for trend		0.001		0.001

Model adjusted for age, gender, BMI, physical activity, HR, current smoker, diabetes, antihypertensive drugs, glucose-lowering drugs, LDL-C, HDL-C, UA, eGFR

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