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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: LPAR5 confers radioresistance to cancer cells associated with EMT activation via the ERK/Snail pathway

Fig. 3

Knockdown of LPAR5 inhibits cancer cell growth and migration and promotes apoptosis. A, B Knockdown efficiency of LPAR5 mediated by siRNA in HeLa cells and A549 cells, as detected by Western blotting and quantified. C, D Effects of knocking down LPAR5 on the proliferation of HeLa cells C and A549 cells (D). E–H Effects of knocking down LPAR5 on the colony-forming abilities of HeLa cells E, F and A549 cells (G, H). I–L Induction of LPAR5 knockdown on apoptosis in HeLa cells I, J and A549 cells (K, L). M–P Effects of knocking down LPAR5 on the migratory abilities of HeLa cells M, N and A549 cells (O, P). Data represent the means ± SDs from three independent experiments. *P < 0.05; **P < 0.01

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