Fig. 1
Transcriptome-wide RNA-seq assay to identify early responsive targets for determining the sensitivity of cancer cells to radiotherapy. A Scatter plot showing RNA expression changes of genes in HeLa cells 2Â h after irradiation compared to unirradiated cells. B KEGG analysis of differentially expressed genes in HeLa cells 2Â h after irradiation compared to unirradiated cells. C Top 10 significantly downregulated PI3K pathway genes in HeLa cells 2Â h after 4Â Gy irradiation compared to unirradiated cells. D Analysis of the 10 genes in panel C in HeLa cells 2Â h after 4Â Gy irradiation compared to 0.5Â h after 4Â Gy irradiation. E GO analysis of differentially expressed genes in HeLa cells 2Â h after irradiation compared to unirradiated cells