Fig. 2

Heatmap of the Spearman’s rank correlation of species and fecal metabolites. 7056 pairs of correlations with 72 bacteria species and 98 fecal metabolites were plotted. Red squares indicate positive associations between these microbial species and clinical indexes. Blue squares indicate negative associations. The statistical significance was denoted inside the squares (*P < 0.05, **P < 0.01)