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Table 1 Characteristics of melanoma patients and normal subject controls of the discovery cohort

From: A novel microRNA signature for the detection of melanoma by liquid biopsy

 

Melanoma patients

Normal controls

(N=16)

(N=22)

Gender

 Male

14 (12,5%)a

10 (45,5%)a

 Female

2 (87,5%) a

12 (54,5%) a

Age (range)

 Male

58 (27-82) b

44 (21-67) b

 Female

54 (50-59) b

48,5 (22-75) b

BRAF status

 Mutated

5 (31,3%) a

 Wild-type

11 (68,7%) a

 

M stage

 M0

2 (12,5%) a

 

 M1a

8 (50%) a

 M1b

1 (6,3%) a

 

 M1c

5 (31,2%) a

 

LDH

 ≤ULN

14 (87,5%) a

 >ULN

2 (12,5%) a

 

Prior lines of therapy

 0

16 (100%) a

 1

0

 
  1. Number of prior lines of therapy: 0 indicated no prior lines of therapy, 1 indicated prior lines of therapy. Enrolled patients did not receive prior lines of therapy
  2. LDH lactate dehydrogenase, UNL upper limit normal
  3. a n (%), b Median (range).