Fig. 4From: A novel microRNA signature for the detection of melanoma by liquid biopsyAbsolute quantification of 4 pEV-microRNA and evaluation of diagnostic performance in an independent internal cohort. A Absolute quantification of circulating levels of 4 pEV-microRNAs (miR-412-3p; miR-507; miR-1203 and miR-362-3p) in an independent internal cohort of normal control (Ctrl) and metastatic melanoma patients (Patients) using ddPCR. Significant differences are highlighted with a starlike symbol (* p value <0.05, **, p value < 0.005), whereas not statistically significant difference with the abbreviation of “ns”. B ROC curves and AUC of 4 pEV -microRNAs in an independent internal cohort (AUC=0.75, p-value=0.008)Back to article page