Fig. 5
From: Silencing eL31 suppresses the progression of colorectal cancer via targeting DEPDC1
DEPDC1 depletion reversed the promotion effects of eL31 overexpression on CRC. A Celigo cell counting assay was employed to show the effects of eL31, shDEPDC1 and eL31 + shDEPDC1 on HCT 116 cell proliferation. B, C The migration rate of cells was detected in eL31, shDEPDC1 and eL31 + shDEPDC1 groups by wound-healing assay (B) and transwell assay (C). D Colony formation assay was used to evaluate the ability of HCT 116 cells to form colonies in eL31, shDEPDC1 and eL31 + shDEPDC1 groups. E The flow cytometry was performed to present the changes of HCT 116 cell apoptosis after transfecting eL31, shDEPDC1 and eL31 + shDEPDC1. NC (shDEPDC1 + eL31): Control; eL31 + NC-shDEPDC1: eL31 overexpression; shDEPDC1 + NC-eL31: DEPDC1 downregulation; shDEPDC1 + eL31: DEPDC1 downregulation and eL31 overexpression. The data are expressed as mean ± SD. ** P < 0.01, *** P < 0.001