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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Alpha-ketoglutarate ameliorates abdominal aortic aneurysm via inhibiting PXDN/HOCL/ERK signaling pathways

Fig. 6

The expression of PXDN was down-regulated in AKG-treated mice. A Volcano plot showing different gene levels in aortic transcriptome. B Heat map showing levels of genes that encoded proteins having typical oxidoreductase activity along with inflammatory response. C RT-qPCR assay was conducted to analyze PXDN level (n = 4). D Gene ontology (GO) analysis. E KEGG pathway analysis. F ICH was conducted to analyze PXDN level (n = 4). G WB assay and quantitative analysis of PXDN level (n = 4)

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