Fig. 4
The ubiquitination of FOCAD at Lys583, Lys587 was probably relevant to the progression of CRC. (A–B) The protein expression of FOCAD and DOCK2 in cancerous and para-cancerous colonic tissues of CRC patients. (C–D) The survival analysis of FOCAD and DOCK2 using the proteomic datasets from CPTAC. (E–F) The increased ubiquitinated sites of FOCAD and DOCK2 in CRC cells. (G–H) The mRNA expression of FOCAD and DOCK2 in cancerous and para-cancerous colonic tissues of CRC patients. (I–J) The correlation between the mRNA and protein levels of FOCAD and DOCK2 in individuals, as analyzed using the datasets from the cbioportal database. (K–L) The protein expression of FOCAD in normal colonic tissues and CRC tissues