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Table 6 Approaches of fertilization -stratified comparison of clinical outcomes

From: Clinical application of noninvasive chromosomal screening for elective single-blastocyst transfer in frozen-thawed cycles

Approaches of fertilization

NICS results

Ratio

Clinical pregnancy rate

Miscarriage rate

Ongoing pregnancy rate

Live birth rate

IVF (n = 111)

Euploid

34.2%(38/111)

57.9%(22/38)

13.6%(3/22)

50.0%(19/38)

50.0%(19/38)

Aneuploid

38.7%(43/111)

37.2%(16/43)

25.0%(4/16)

25.6%(11/43)

25.6%(11/43)

Chaotic/NA

27.0%(30/111)

63.3%(19/30)

15.8%(3/19)

53.3%(16/30)

53.3%(16/30)

p-value

 

0.055

0.681

0.025

0.025

ICSI (n = 99)

Euploid

51.5%(51/99)

54.9%(28/51)

17.9% (5/28)

45.1%(23/51)

43.1%(22/51)

Aneuploid

25.3%(25/99)

16.0%(4/25)

0(0/4)

16.0%(4/25)

16.0%(4/25)

Chaotic/NA

23.2%(23/99)

56.5%(13/23)

23.1%(3/13)

43.5%(10/23)

43.5%(10/23)

p-value

 

0.003

0.721

0.038

0.050

P value for approaches of fertilization subgroups

0.031

0.393(51.4%vs 45.5%)

0.975(17.5%vs17.8%)

0.547(41.4%vs37.4%)

0.451(41.4%vs36.4%)