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Table 5 Embryonic days -stratified comparison of clinical outcomes

From: Clinical application of noninvasive chromosomal screening for elective single-blastocyst transfer in frozen-thawed cycles

Embryonic days

NICS results

Ratio

Clinical pregnancy rate

Miscarriage rate

Ongoing pregnancy rate

Live birth rate

D5 (n = 156)

Euploid

40.4%(63/156)

68.3%(43/63)

9.3%(4/43)

61.9%(39/63)

61.9%(39/63)

Aneuploid

29.5%(46/156)

39.1%(18/46)

22.2%(4/18)

28.3%(13/46)

28.3%(13/46)

Chaotic/NA

30.1%(47/156)

61.7%(29/47)

20.7%(6/29)

48.9%(23/47)

48.9%(23/47)

p-value

 

0.008

0.242

0.002

0.002

D6 (n = 54)

Euploid

48.1%(26/54)

26.9%(7/26)

57.1%(4/7)

11.5%(3/26)

7.7%(2/26)

Aneuploid

40.7%(22/54)

9.1%(2/22)

0(0/2)

9.1%(2/22)

9.1%(2/22)

Chaotic/NA

11.1%(6/54)

50.0%(3/6)

0(0/3)

50.0%(3/6)

50.0%(3/6)

p-value

 

0.055

0.180

0.072

0.046

P value for embryonic days subgroups

0.019

 < 0.001(57.7%vs 22.2%)

0.217(15.6%vs33.3%)

 < 0.001(48.1%vs14.8%)

 < 0.001(48.1%vs13.0%)