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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Inhibition of XPO1 with KPT-330 induces autophagy-dependent apoptosis in gallbladder cancer by activating the p53/mTOR pathway

Fig. 3

XPO1 inhibitor KPT-330 induced changes in multiple tumor pathways related to the transport function of XPO1. A Heatmap and Go function analysis of differential genes (|\({Log}_{2}FC\)|≥ 2 and Q-value ≤ 0.05) of NOZ after KPT-330 treatment for 48 h. B GO cellular component analysis of differential genes. C KEGG pathway analysis of differential genes. D Apoptosis pathway GSEA analysis of differential genes. E. p53 pathway GSEA analysis of differential genes

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Journal of Translational Medicine

ISSN: 1479-5876

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