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Table 1 The internal standard information

From: Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia

Serial number

Classification

Glass

Name

Internal standard concentration ÎĽM (ÎĽmol/L)

1

Phosphatidylcholine

PC

PC(16:0/16:0)-d9

0.2

2

Oxidized lipids

Eicosanoid

5S-HETE-d8

0.04

3

Free fatty acid

FFA

Arachidonic Acid-d8

0.2

4

Acyl carnitine

CAR

CAR(16:0)-d3

0.04

5

Cholesterol ester

CE

CE(18:1)-d7

2

6

ceramide

Cer

Cer(d18:1/15:0)-d7

0.1

7

ceramide

Cer

Cer(d18:1-d7/16:0)

0.1

8

ceramide

Cer

Cer(d18:1-d7/18:0)

0.1

9

ceramide

Cer

Cer(d18:1-d7/24:0)

0.1

10

ceramide

Cer

Cer(d18:1-d7/24:1)

0.1

11

phytoceramide

Cert

Cer(t18:0/22:0-d3)

0.1

12

Ceramide 1-phosphate

CerP

CerP(d18:1/8:0)

0.4

13

cholesterol

Cho

cholesterol-d7

5

14

Coenzyme Q

CoQ

CoQ10-d9

0.2

15

diglyceride

DG

DG(17:0/17:0)-d5

0.2

16

Free fatty acid

FFA

FFA(16:0)-d31

0.2

17

Bile acid

BA

GCDCA-d4

0.2

18

Sugar sheath fat

HexCer

HexCer(d18:1-d5/18:0)

0.4

19

Lysophosphatidic acid

LPA

LPA(17:0)

0.5

20

Lysophosphatidylcholine

LPC

LPC(15:0)-d5

0.2

21

Lysophosphatidylcholine

LPC

LPC(16:0)-d31

0.2

22

Lysophosphatidylcholine

LPC

LPC(17:0)-d5

0.2

23

Lysophosphatidylcholine

LPC

LPC(18:1)-d7

0.2

24

Lysophosphatidylethanolamine

LPE

LPE(15:0)-d5

0.2

25

Lysophosphatidylethanolamine

LPE

LPE(18:1)-d7

0.2

26

Lysophosphatidyl glycerol

LPG

LPG(15:0)-d5

0.2

27

Lysophosphatidyl glycerol

LPG

LPG(17:1)

0.2

28

Lysophosphatidylinositol

LPI

LPI(17:1)

0.2

29

Lysophosphatidylserine

LPS

LPS(17:1)

0.2

30

monoglyceride

MG

MG(18:1-d7)

0.5

31

Phosphatidic acid

PA

PA(17:0/17:0)

0.5

32

Phosphatidylcholine

PC

PC(15:0/18:1(d7))

0.2

33

Phosphatidylcholine

PC

PC(16:0-d31/18:1)

0.2

34

Phosphatidylcholine

PC

PC(14:0/14:0)-d9

0.2

35

Phosphatidylethanolamine

PE

PE(15:0/18:1(d7))

0.2

36

Phosphatidylethanolamine

PE

PE(16:0-d31/18:1)

0.2

37

Phosphatidylethanolamine

PE

PE(17:0/14:1)-d5

0.2

38

Phosphatidylethanolamine

PE

PE(17:0/18:1)-d5

0.2

39

Phosphatidylethanolamine

PE

PE(17:0–22:4)-d5

0.2

40

Phosphatidyl glycerol

PG

PG(15:0/18:1(d7))

0.4

41

Phosphatidyl glycerol

PG

PG(16:0/d31/18:1)

0.4

42

Phosphatidylinositol

PI

PI(16:0-d31/18:1)

0.2

43

Phosphatidyl methanol

PMeOH

PMeOH(16:0/16:0)

0.1

44

Phosphatidylserine

PS

PS(15:0/18:1(d7))

0.4

45

Phosphatidylserine

PS

PS(16:0(d31)/18:1)

0.4

46

Phosphatidylserine

PS

PS(16:0/16:0)-d9

0.4

47

sphingomyelin

SM

SM(d18:1/18:1)-d9

0.2

48

sphingomyelin

SM

SM(d18:1/20:1)-d9

0.2

49

sphingomyelin

SM

SM(d18:1/22:1)-d9

0.2

50

sphingomyelin

SM

SM(d18:1-d9/15:0)

0.2

51

sphingosine

SPH

SPH(18:1)-d7

0.04

52

triglycerides

TG

TG(14:0/16:1/14:0)-d5

0.2

53

triglycerides

TG

TG(16:0–15:1–16:0)-d5

0.2

54

triglycerides

TG

TG(17:0/17:1/17:0)-d5

0.2