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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia

Fig. 2

Effects of BBR on serum TC, TG and LDL-C concentrations (A). Compared with NFD group, *p < 0.05, **p < 0.01, ***p < 0.001; Compared with HFD group, #p < 0.05, ##p < 0.01). Data are presented as mean ± SD (n = 6). Liver H&E staining (magnification, 400 × and 1000 ×) (B). Liver Oil red O staining (magnification, 400 ×) and the quantification of lipid droplet area ratio assessed by Oil red O staining (C). Black arrows indicate the cytoplasmic vacuolation and the aggregation of red lipid droplets, respectively. Compared with NFD group, ***p < 0.001; Compared with HFD group, ###p < 0.001)

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