Table 2 The significantly enriched 8 KEGG pathways based on the differentially expressed proteins (CSCC vs. healthy control; CSCC vs. Bowen disease)
CSCC vs. healthy control | CSCC vs. Bowen disease | – log10(p value) | |||
|---|---|---|---|---|---|
KEGG pathway | P value | – log10(p value) | KEGG pathway | P value | |
hsa03010 Ribosome | 4.39*10–9 | 8.36 | hsa04141 Protein processing in endoplasmic reticulum | 3.28*10–7 | 6.48 |
hsa04974 Protein digestion and absorption | 7.64*10–6 | 5.12 | hsa05130 Pathogenic Escherichia coli infection |  < 0.001 | 3.87 |
hsa05171 Coronavirus disease -COVID-19 | 1.24*10–5 | 4.91 | hsa05146 Amoebiasis | 0.004 | 2.34 |
hsa04512 ECM-receptor interaction | 1.43*10–5 | 4.84 | hsa04810 Regulation of actin cytoskeleton | 0.004 | 2.33 |
hsa04141 Protein processing in endoplasmic reticulum | 6.18*10–5 | 4.21 | hsa00500 Starch and sucrose metabolism | 0.007 | 2.11 |
hsa00030 Pentose phosphate pathway |  < 0.001 | 3.55 | hsa04530 Tight junction | 0.008 | 2.05 |
hsa04510 Focal adhesion |  < 0.001 | 3.07 | hsa04144 Endocytosis | 0.009 | 2.03 |
hsa04151 PI3K-Akt signaling pathway | 0.001 | 2.99 | hsa04666 Fc gamma R-mediated phagocytosis | 0.010 | 1.99 |