Fig. 6
From: Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation
miR-210-3p promotes fibroblast proliferation and collagen synthesis by targeting GPD1L. A GPD1L was silenced by siRNAs in atrial fibroblasts. The protein B, C expression levels of Collagen III, TGFβ1 and α-SMA and mRNA (D) expression levels of α-SMA, Collagen I and TGFβ1 in atrial fibroblasts (*P < 0.05, **P < 0.01, and ***P < 0.001). E CCK8 assay to detect the effect of miR-210-3p and GPD1L on the proliferation of atrial fibroblasts (##P < 0.05 compared with NC, **P < 0.05 compared with miR-210-3p mimic + GPD1L). F Immunofluorescence staining to detect the relative expression levels of α-SMA (green) and DAPI (blue) in atrial fibroblasts. Scale bar: 50 μm