Fig. 6From: Radiated glioblastoma cell-derived exosomal circ_0012381 induce M2 polarization of microglia to promote the growth of glioblastoma by CCL2/CCR2 axisThe radiation induced C/EBPB to increase the level of circ_0012381 and CCR2 in glioma cells. A Radiation induced the expression of C/EBPB in U251 cells. B The expression of CCR2 decreased after knocked down C/EBPB. C The level of circ_0012381 decreased after knocked down C/EBPB. D ChIP assay identified that C/EBPB transcriptionally regulated the level of circ_0012381 in U251 cells. E ChIP assay identified that C/EBPB transcriptionally regulated the expression of CCR2 in U251 cellsBack to article page