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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: TSLP promoting B cell proliferation and polarizing follicular helper T cell as a therapeutic target in IgG4-related disease

Fig. 2

The effect of TSLP on B cells in IgG4-RD. CD19+ B cells from IgG4-RD patients were stimulated with IL-4, anti-IgM, CD40L, with or without TSLP. Proliferation quantified by Ki-67 (A, B), apoptosis measured by 7-AAD and Annexin-V (C, D), and B cell subsets (E, F) were assessed on 5 days. Supernatant IgG and IgG4 levels on 7 days were quantified by ELISA (G). *p < 0.05

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