Table 1 Patients’ characteristics
All patients (N = 556) | Nephrectomy (N = 490) | No-nephrectomy (N = 66) | p value | |
|---|---|---|---|---|
Gender | ||||
Male | 391 (70.3) | 347 (70.8) | 44 (66.7) | |
Female | 165 (29.7) | 143 (29.2) | 22 (33.3) | 0.49 |
Age (median, range) | 63 (18–85) | 62 (18–85) | 66 (40–84) | 0.004 |
Histology | ||||
Clear cell | 464 (84.1) | 407 (83.4) | 57 (89.1) | |
Non clear cell | 88 (15.9) | 81 (16.6) | 7 (10.9) | 0.34 |
Treatment line | ||||
2nd line | 384 (69.1) | 333 (68.0) | 51 (77.3) | |
3rd line | 118 (21.2) | 106 (21.6) | 12 (18.2) | |
> 3rd line | 54 (9.7) | 51 (10.4) | 3 (4.5) | 0.21 |
NLR (median, IQR) | 2.8 (1.9–4.3) | 2.8 (1.9–4.0) | 3.7 (2.5–5.0) | |
< 3.2 | 331 (59.5) | 306 (62.5) | 25 (37.8) | < 0.001 |
≥ 3.2 | 225 (40.5) | 184 (37.6) | 41 (62.1) | |
Bone metastases | ||||
Yes | 361 (64.9) | 331 (67.8) | 30 (45.5) | 0.001 |
No | 195 (35.1) | 159 (32.5) | 36 (54.5) | |
IMDC score | ||||
Favourable | 129 (23.2) | 127 (25.9) | 2 (3.0) | < 0.001 |
Intermediate | 358 (64.4) | 312 (63.7) | 46 (69.7) | |
Poor | 69 (12.4) | 51 (10.4) | 18 (27.3) | |
Meet-URO score | ||||
1 | 86 (15.5) | 84 (17.1) | 2 (3.1) | < 0.001 |
2 | 193 (34.7) | 184 (37.6) | 9 (13.6) | |
3 | 153 (27.5) | 129 (26.3) | 24 (36.4) | |
4 | 97 (17.5) | 77 (15.7) | 20 (30.3) | |
5 | 27 (4.9) | 16 (3.3) | 11 (16.7) | |