Fig. 2
From: The potential of mecciRNA in hepatic stellate cell to regulate progression of nonalcoholic hepatitis
mecciRNAs Account for Half of Downregulated circRNAs in HSCs of NASH. A The volcano plot shows upregulated (red) and downregulated (blue) circRNAs in HSCs of NASH patients (GSE134146), in which 4 mecciRNAs were marked. P-value < 0.05 and |Log2FC|≥ 1.5. B The chromosome locations of differentially expressed circRNAs, in which mecciRNAs were highlighted. C The numbers of differentially expressed nucleus-encoded and mitochondria-encoded circRNAs were 24 and 4, respectively (left panel). And the proportion of mecciRNAs in the total circRNomics is shown (right panel). D The name, length, location of differentially expressed mecciRNAs in the mitochondrial genome. E The expression levels of 4 mecciRNAs in cytosolic and mitochondrial fractions of LX-2 cells were determined by RT-qPCR. GAPDH and MTCO2 mRNA served as the cytosolic and mitochondrial control, respectively