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Table 1 Clinicopathological characteristics

From: Low mitochondrial DNA copy number induces chemotherapy resistance via epithelial-mesenchymal transition by DNA methylation in esophageal squamous cancer cells

No. of patients

 

mtDNA copy number ≧ median (n = 45)

mtDNA copy number  <  median (n = 43)

p value

Age

< 70/70≧

34/11

24/19

0.051

Sex

Male/female

36/9

35/8

0.868

Histology

wel, mod/por

35/10

31/12

0.538

cT

1–2/3, 4

6/39

9/34

0.344

cN

0/1–3

7/38

9/34

0.514

cM

0/1

41/4

32/11

0.049

cStage

I, II/III, IV

11/34

11/32

0.902

NAC regimen

ACF/DCF

34/11

27/16

0.194

Lymphatic invasion

−/+ 

7/38

5/38

0.592

Venous invasion

−/+ 

28/17

33/10

0.140

Pathological response

0, 1a/1b, 2

25/20

34/9

0.019

pT

1–2/3, 4

16/29

18/25

0.544

pN

0/1–3

17/28

13/30

0.455

pM

0/1

39/6

37/6

0.933

pStage

I, II/III, IV

21/24

17/26

0.500

  1. NAC neoadjuvant chemotherapy, wel well differenced type, mod moderately differenced type, por poor differenced type