Journal of Translational Medicine

Table 6 Interactions of the engineered vaccine with TLR2 and TLR4. Analysis of interactions was performed by DIMPLOT program from LigPlot + v2.2.4

From: In silico designing of a novel epitope-based candidate vaccine against Streptococcus pneumoniae with introduction of a new domain of PepO as adjuvant

ODAC -TLR2					ODAC -TLR4
ODAC residues		TLR2 residues		H-bond distance	ODAC residues		TLR4 residues		H-bond distance
Name	No	Name	No	H-bond distance	Name	No	Name	No	H-bond distance
Met	1	Pro	320	2.88	Thr	2	Asp	95	2. 90
Trp	50	Arg	321	2.97	Arg	3	Leu	119	2.83
Thr	2	Arg	321	2.61	Asp	59	Asn	143	2.91
Trp	50	Tyr	323	281	Arg	70	Glu	169	2.78
Asp	6	Lys	347	2.64	Trp	16	Asn	173	2.86
Asp	6	Lys	347	2.54	Arg	70	Gln	200	2.77
Glu	40	Glu	374	3.08	Arg	70	Gln	200	2.62
Tyr	9	Gln	396	2.74	His	368	Gln	200	2.99
Asp	10	Gln	396	2.75	His	369	Glu	225	2.78
Asp	34	Lys	404	2.75	His	372	Arg	227	2.84
Gln	37	Lys	404	2.77	Asp	10	Lys	150	2.64
Asp	36	Ser	424	2.82	Glu	15	Lys	150	2.71
Asn	13	Arg	447	2.69
Asn	13	Arg	447	2.71
Glu	58	Arg	321	2.69

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ISSN: 1479-5876

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