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Table 1 Baseline characteristics of the enrolled volunteers

From: Probiotics ameliorate IgA nephropathy by improving gut dysbiosis and blunting NLRP3 signaling

Characteristics

HC

IgAN

P value

Numbers

25

35

 

Age (years)

31.5 ± 5.4

33.5 ± 6.2

0.10

Male (%)

12 (48%)

17 (48.6)

1.00

BMI (kg/m2)

22.5 ± 2.1

23.3 ± 3.5

0.56

SBP (mmHg)

111.6 ± 6.2

125.1 ± 16.5

 < 0.01

DBP (mmHg)

69.4 ± 3.2

85.3 ± 9.9

 < 0.01

sCr (µmol/L)

61.0 (55.0–70.0)

80.0 (58.5–106.0)

 < 0.01

eGFR (mL/min/1.73 m2)

116.9 (114.0–125.9)

94.1 (70.8–118.8)

 < 0.01

Urine protein (g/24 h)

0.06 ± 0.03

0.98 ± 0.63

 < 0.01

Urine RBCs (/HPF)

0 (0–2)

13 (5–60)

 < 0.01

  1. HC healthy controls, IgAN IgA nephropathy, BMI body mass index, SBP systolic pressure, DBP diastolic blood pressure, sCr serum creatinine, eGFR estimated glomerular filtration rate, RBCs red blood cells, HPF high-power field