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Table 1 Baseline characteristics of the enrolled volunteers

From: Probiotics ameliorate IgA nephropathy by improving gut dysbiosis and blunting NLRP3 signaling

Characteristics HC IgAN P value
Numbers 25 35  
Age (years) 31.5 ± 5.4 33.5 ± 6.2 0.10
Male (%) 12 (48%) 17 (48.6) 1.00
BMI (kg/m2) 22.5 ± 2.1 23.3 ± 3.5 0.56
SBP (mmHg) 111.6 ± 6.2 125.1 ± 16.5  < 0.01
DBP (mmHg) 69.4 ± 3.2 85.3 ± 9.9  < 0.01
sCr (µmol/L) 61.0 (55.0–70.0) 80.0 (58.5–106.0)  < 0.01
eGFR (mL/min/1.73 m2) 116.9 (114.0–125.9) 94.1 (70.8–118.8)  < 0.01
Urine protein (g/24 h) 0.06 ± 0.03 0.98 ± 0.63  < 0.01
Urine RBCs (/HPF) 0 (0–2) 13 (5–60)  < 0.01
  1. HC healthy controls, IgAN IgA nephropathy, BMI body mass index, SBP systolic pressure, DBP diastolic blood pressure, sCr serum creatinine, eGFR estimated glomerular filtration rate, RBCs red blood cells, HPF high-power field