Fig. 2
From: Probiotics ameliorate IgA nephropathy by improving gut dysbiosis and blunting NLRP3 signaling
Probiotics could improve the structure of the intestinal flora in mice with IgAN. a The protocol for constructing an IgAN mouse model. b The renal pathology of wild-type mice (WC group) and IgAN mice (W-IgAN group) indicated that the IgAN model was successfully established. c The alpha diversity indexes of mice in the WC group and the W-IgAN group. d Beta diversity analysis of intestinal flora of IgAN mice and normal control mice. e Species composition analysis of IgAN mice and normal control mice at the genus level. f, g Comparison of abundance of intestinal Lactobacillus and Bifidobacterium in IgAN mice and normal control mice. h, i Analysis of alpha and beta diversity in IgAN mice treated with probiotics (W-IgAN + B group). j, k Venn diagram and ternary analysis of intestinal flora in IgAN mice treated with probiotics. l–p Comparison of the abundance of Lactobacillus, Bifidobacterium, Allobaculum, Helicobacter and Alloprevotella among the mice in the WC, W-IgAN and W-IgAN + B groups. * 0.01 < P ≤ 0.05. ** 0.001 < P ≤ 0.01. *** P ≤ 0.001