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Table 4 The univariate and multivariate analysis of VIPR1 and clinicopathological features of HCC patients

From: lncRNA-AC079061.1/VIPR1 axis may suppress the development of hepatocellular carcinoma: a bioinformatics analysis and experimental validation

Characteristics

Total(N)

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

P value

Hazard ratio (95% CI)

P value

T stage

370

    

 T1&T2

277

Reference

   

 T3&T4

93

2.598 (1.826–3.697)

 < 0.001

2.025 (0.274–14.977)

0.489

N stage

258

    

 N0

254

Reference

   

 N1

4

2.029 (0.497–8.281)

0.324

  

M stage

272

    

 M0

268

Reference

   

 M1

4

4.077 (1.281–12.973)

0.017

1.875 (0.574–6.128)

0.298

Pathologic stage

349

    

 Stage I&Stage II

259

Reference

   

 Stage III&Stage IV

90

2.504 (1.727–3.631)

 < 0.001

1.404 (0.191–10.315)

0.739

Histologic grade

368

    

 G1&G2

233

Reference

   

 G3&G4

135

1.091 (0.761–1.564)

0.636

  

Gender

373

    

 Female

121

Reference

   

 Male

252

0.793 (0.557–1.130)

0.200

  

Age

373

    

  ≤ 60

177

Reference

   

  > 60

196

1.205 (0.850–1.708)

0.295

  

Vascular invasion

317

    

 No

208

Reference

   

 Yes

109

1.344 (0.887–2.035)

0.163

  

VIPR1

373

    

 Low

186

Reference

   

 High

187

0.668 (0.472–0.945)

0.023

0.584 (0.377–0.904)

0.016