Fig. 7From: Identification of LARS as an essential gene for osteosarcoma proliferation through large-Scale CRISPR-Cas9 screening database and experimental verificationThe function of LARS in osteosarcoma cells. A The CERES score of LARS in 8 osteosarcoma cell lines. B GSEA analysis suggested that the high expression of LARS is related to the cell cycle. C, D The mRNA expression of LARS in LARS knockdown Saos-2 cells (C) and LARS knockdown U-2 OS cells (D). E, F The protein expression of LARS in LARS knockdown Saos-2 cells (E) and LARS knockdown U-2 OS cells (F). G, H Knockdown LARS inhibited the proliferation of G Saos-2 and H U-2 OS cells detected by CCK8. **p < 0.01Back to article page