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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Evidence of pyroptosis and ferroptosis extensively involved in autoimmune diseases at the single-cell transcriptome level

Fig. 5

Pyroptosis involved in the pathological process of SSc-ILD. Expression levels of pyroptosis-related genes in different cell types, such as alveolar type 1&2 cells (A), club/gobelet/basal cells (B), smooth muscles/pericytes (C), and ECs (D) across matched samples. (E) Selected important genes are shown in monocle2 produced pseudotime trajectory plot in different representative samples. (F) Schematic depiction of typical GSDM gene expression patterns within different cell types under pathological SSc-ILD condition

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