Table 1 Correlation between clinicopathological characteristics and NMF typing in the TCGA database
Characteristics | C1 (N = 185) | C2 (N = 316) | Total (N = 501) | P-value |
|---|---|---|---|---|
Age | ||||
 Mean ± standard deviation | 66.33 ± 8.74 | 67.71 ± 8.46 | 67.20 ± 8.58 | 0.0836 |
 Median [min, max] | 68 [39, 85] | 68 [40, 90] | 68 [39, 90] |  |
Gender | ||||
 Female | 36 (7.19%) | 94 (18.76%) | 130 (25.95%) | 0.0112* |
 Male | 149 (29.74%) | 222 (44.31%) | 371 (74.05%) | |
T | ||||
 T1 | 36 (7.19%) | 78 (15.57%) | 114 (22.75%) | 0.5468 |
 T2 | 112 (22.36%) | 181 (36.13%) | 293 (58.48%) | |
 T3 | 29 (5.79%) | 42 (8.38%) | 71 (14.17%) | |
 T4 | 8 (1.60%) | 15 (2.99%) | 23 (4.59%) | |
N | ||||
 N0 | 112 (22.36%) | 207 (41.32%) | 319 (63.67%) | 0.1161 |
 N1 | 57 (11.38%) | 74 (14.77%) | 131 (26.15%) | |
 N2 | 16 (3.19%) | 24 (4.79%) | 40 (7.98%) | |
 N3 | 0 | 5 (1.00%) | 5 (1.00%) | |
 Nx | 0 | 6 (1.20%) | 6 (1.20%) |  |
M | ||||
 M0 | 149 (29.74%) | 262 (52.30%) | 411 (82.04%) | 0.4213 |
 M1 | 1 (0.20%) | 6 (1.20%) | 7 (1.40%) | |
 Mx | 34 (6.79%) | 45 (8.97%) | 79 (15.76%) |  |
 Unknown | 1 (0.20%) | 3 (0.60%) | 4 (0.80%) |  |
Stage | ||||
 Stage I | 80 (15.97%) | 164 (32.73%) | 244 (48.70%) | 0.1160 |
 Stage II | 68 (13.57%) | 94 (18.76%) | 162 (32.34%) | |
 Stage III | 35 (6.99%) | 49 (9.78%) | 84 (16.77%) | |
 Stage IV | 1 (0.20%) | 6 (1.20%) | 7 (1.40%) | |
 Unknown | 1 (0.20%) | 3 (0.60%) | 4 (0.80%) |  |
IPTS groups | ||||
 High score | 52 (10.38%) | 254 (50.70%) | 306 (61.08%) | < 0.0001**** |
 Low score | 133 (26.55%) | 62 (12.38%) | 195 (38.92%) | |