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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: A fetal fraction enrichment method reduces false negatives and increases test success rate of fetal chromosome aneuploidy detection in early pregnancy loss

Fig. 3

FF and test failures rate association with GA between two different NIPS methods. A Compared to the standard NIPS test, mean FF was increased across different GAs in total samples (6.5% vs 14.6%, 9.4% vs 16.4%, 8.9% vs 20.4%, and 10.2% vs 26.2%). B Compared to the standard NIPS test, test success rate was increased across different GAs in total samples (84.6% vs 92.3%, 85.1% vs 100%, 87.5% vs 100%, and 87.8% vs 100%). C Compared to the standard NIPS test, mean FF was increased across different GAs in pregnant women with male fetuses using size-selection NIPS (4.3% vs 8.1%, 5.9% vs 13.0%, 6.3% vs 17.7%, and 8.8% vs 25.8%). D Compared to the standard NIPS test, test success rate was increased across different GAs in pregnant women with male fetuses using size-selection enrichment (63.6% vs 81.8%, 72.7% vs 100%, 77.4% vs 100%, and 86.8% vs 100%)

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Journal of Translational Medicine

ISSN: 1479-5876

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