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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: The RNA-binding protein PCBP1 represses lung adenocarcinoma progression by stabilizing DKK1 mRNA and subsequently downregulating β-catenin

Fig. 1

Identification of the prognostic and potential biological value of PCBP1. A Heatmap of differentially expressed genes between cancer and adjacent tissues in LUAD patients and the early death group and long-term survival group. B Kaplan–Meier survival curves of overall survival between high PCBP1 expression and low PCBP1 expression patients from TCGA and GSE19188. C PCBP1 expression between patients with distant metastasis and patients without metastasis. D PCBP1 expression in LUAD patients with different TNM stages. E IHC staining of human LUAD tissues and paired adjacent normal tissues; scale bars, 100 μm. F, G Comparison of PCBP1 detected by IHC staining (F) and qPCR (G) between tumour and peritumoral tissues and patients with different tumour sizes, N staging and tumour stages. H Kaplan–Meier analysis of overall survival was stratified by protein expression levels of PCBP1. I Kaplan–Meier analysis of overall survival was stratified by mRNA expression levels of PCBP1. *p < 0.05; **p < 0.01; ns, not significant

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