Fig. 2

GAS6-AS1 promotes the proliferation, migration and invasion of CRC cells. A The expression of GAS6-AS1 of the CRC cell lines were detected via qRT-PCR. B After upregulation of GAS6-AS1 in HT29 cell lines, the efficiency was verified via qRT-PCR. C After downregulation of GAS6-AS1 in LoVo cell lines, interference efficiency was verified via qRT-PCR. D After upregulation of GAS6-AS1, CCK8 assay revealed that the proliferation of HT29 cells was significantly enhanced. E After downregulation of GAS6-AS1, CCK8 assay revealed that the proliferation of LoVo cells was significantly decreased. F After upregulation of GAS6-AS1, EdU assay revealed that the proliferation of HT29 cells was significantly enhanced. G After downregulation of GAS6-AS1, EdU assay revealed that the proliferation of LoVo cells was significantly decreased. H–M Overexpression of GAS6-AS1 significantly enhanced the migration H, J and invasion L ability of HT29 cells. Knockdown of GAS6-AS1 significantly suppressed the migration I, K and invasion M ability of LoVo cells. (scale bar: 200 μm for EdU assay, 50 μm for wound healing assay, 100 μm for Transwell assay). * P < 0.05, ** P < 0.01, *** P < 0.001, **** P < 0.0001