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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: IGF2BP1-regulated expression of ERRα is involved in metabolic reprogramming of chemotherapy resistant osteosarcoma cells

Fig. 3

The mRNA stability of ERRα increased in Dox-resistant OS cells. The levels of mRNA (a) and protein (b) of ERRα in OS parental and Dox-resistant cells; c promoter activities in OS parental and Dox-resistant cells pre-transfected with vector control or pGL3-ERRα reporter; d the precursor ERRα mRNA in OS parental and Dox-resistant cells were checked by qRT-PCR; e, f OS parental and Dox-resistant cells were treated with Act-D for different time periods, the mRNA of ERRα was checked by qRT-PCR. Data are presented as means ± SD from three independent experiments. **p < 0.01 by Student’s t test

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